AMELOBLASTOMA HISTOPATHOLOGY PDF

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This article has been cited by other articles in PMC. Abstract The aim of the present study is to examine all cases of intraosseous benign ameloblastomas treated between and in a single institution and to look for a possible correlation between the histopathological aspects and the demographical and clinical parameters, as well as the treatment outcome. The data of a total number of 44 patients were retrieved from the records. Nine patients were excluded because of doubt about the correct diagnosis 8 patients or because of an extra-osseous presentation 1 patient.

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Correspondence: Atarbashi-Moghadam S, Dept. Abstract Ameloblastomas demonstrate various clinical and microscopic patterns. Granular cell subtype is a rare variant especially when both the inner and peripheral layers of tumoral islands composed exclusively of eosinophilic granular cells. The purpose of this case report is to present a unique case of cystic ameloblastoma with an unusual radiographic and microscopic pattern affecting a year-old female.

Awareness of these rare histopathologic features for oral pathologist is essential to help correct diagnosis. Keywords: Ameloblastoma , Oral Neoplasm , Odontogenic tumor , Mandible Introduction Ameloblastoma is a benign, locally aggressive epithelial odontogenic neoplasm, which reveals several different microscopic variants[ 1 - 3 ]. It is divided into three groups of solid, cystic unicystic , and peripheral. Unicystic ameloblastomas are seen more often in younger patients during the second decades of life.

The posterior mandible is the most common location[ 4 - 5 ]. The lesion is often asymptomatic, although large lesions may cause a painless swelling of the jaws[ 5 ].

Unicystic ameloblastoma is classified into three microscopic groups including luminal, intraluminal plexiform , and mural. In luminal variant, the tumor is confined to the luminal surface of the cyst. In the intraluminal variant, one or more nodules of ameloblastoma project from the cystic lining into the lumen of the cyst. In mural type, the fibrous wall of the cyst is infiltrated by typical follicular or plexiform ameloblastoma[ 4 - 6 ].

Although luminal and intraluminal ameloblastoma may be treated by enucleation, radical surgery is the treatment of choice for mural ameloblastoma4.

Granular cell subtype is rare variant[ 1 - 3 ]. To the best of our knowledge, granular cytoplasmic changes are seen in the stellate reticulum regions of the ameloblastomatous follicles and interlacing cords and nests.

Rarely granular changes can also be detected in peripheral ameloblastic cells[ 1 , 6 ]. Failure to recognize ameloblastoma patterns is caused confusion for pathologist; therefore, the aim of this study was to present a rare challenging case of granular cell mural ameloblastoma in the posterior mandible of year-old female.

Intraoral examination revealed a swelling in the posterior area of right mandible. There was no cervical lymphadenopathy and the laboratory data was unremarkable. Given the radiographic feature, the diagnosis of ameloblastoma was considered. To make a final diagnosis, incisional biopsy was performed under local anesthesia.

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Mandibular Mural Ameloblastoma with Unusual Histopathologic Features: a Rare Challenging Case

Brajind It shows equal sex predilection with no specific racial predominance. The aim of the present study is to examine all cases of intraosseous benign ameloblastomas treated between and in hidtopathology single institution and to look for a possible correlation between the histopathological aspects and the demographical and clinical parameters, as well as the treatment outcome. Robinson has defined it as: Differential diagnosis of conventional multicystic ameloblastoma Malignant ameloblastoma Also called metastasizing ameloblastoma Identical histology but with metastasis Ameloblastic carcinoma Variable features of amelobastoma: The incidence of ameloblastomas is estimated at 0,5 per million population per year, although in some parts in the world, amelpblastoma. However, this term has become obsolete and has to be avoided. J Oral Maxillofac Surg. Peripheral ameloblastomas are not aggressive clinically and can be managed by local excision. Services on Demand Journal.

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Ameloblastoma

Correspondence: Atarbashi-Moghadam S, Dept. Abstract Ameloblastomas demonstrate various clinical and microscopic patterns. Granular cell subtype is a rare variant especially when both the inner and peripheral layers of tumoral islands composed exclusively of eosinophilic granular cells. The purpose of this case report is to present a unique case of cystic ameloblastoma with an unusual radiographic and microscopic pattern affecting a year-old female.

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Fenrizragore Adenomatoid odontogenic tumor Keratocystic odontogenic tumour. Histological typing of odontogenic tumors. Histkpathology, it is seen that the granules consist of pleomorphic, osmiophilic, lysosome like organelles. As the tumor enlarges, it forms a hard swelling and later may cause thinning of the cortical bone resulting in an egg shell crackling which can be elicited. There are minimal areas of starry reticulum and in some regions ameloblasts are not evident.

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